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– Reusable and sterilizable
– Needle-style design
– Suitable for gene and drug transfer in in-vivo, ex-vivo, and in-ovo conditions

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Introduction to Gene-Electrodes

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Gene-electrodes are reusable, needle-style electrodes designed and manufactured by Pars Tarava, the first producer of electroporation devices in Iran. These electrodes are optimized for various applications, including gene and drug transfer in in-vivo (in living organisms), ex-vivo (outside the body), and in-ovo (inside eggs) conditions. One of the standout features of these electrodes is their engineered design and reusability, which reduces costs, making them highly suitable for research in medical, biomedical, genetic, and drug delivery fields.

Applications of Gene-Electrodes

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Electroporation is an efficient method for transferring genetic materials (such as DNA and RNA) or drug compounds into cells. In this method, controlled electric pulses create temporary pores in the cell membrane, allowing the target molecules to enter. The unique design of gene-electrodes enables this process with high precision and efficiency.

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Gene-electrodes are used for gene and drug transfer through electroporation in various conditions. In summary, the key applications are as follows:

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• In-Vivo Electroporation: Direct transfer of genetic or pharmaceutical materials into living tissues (such as muscle, liver, or other organs) within the organism.
• Ex-Vivo Electroporation: Used on cultured tissues or tissue samples removed from the body, facilitating gene transfer and manipulation outside the body.
• In-Ovo Electroporation: Widely used in embryology research, particularly for gene transfer to avian embryos inside the egg. This method allows for the evaluation of genetic changes during the early stages of embryo development.

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Compatibility with Pars Tarava Devices

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Pars Tarava is the first and only manufacturer of electroporation devices in Iran. Gene-electrodes are fully compatible with the electroporation devices produced by this company. With standard connectors (banana plug to microgripper cable), these electrodes can be directly connected to electroporation devices without the need for additional converters. This makes them easy to use in both laboratory and clinical settings.

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Advantages and Technical Features

The standout advantages and technical features of gene-electrodes compared to similar options include:

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– Reusability and Sterilization: These electrodes are made from high-quality stainless steel, allowing for easy sterilization and repeated use without compromising performance. This significantly reduces research costs and enhances laboratory productivity.
– Needle-Style Design: The needle-style design of these electrodes enables precise targeting of deep tissues (such as muscle, skin, or tumors) in in-vivo conditions. They are also ideal for ex-vivo applications (such as gene transfer to cultured cells) and in-ovo (embryo gene transfer).
– Long Pulse Life: The gene-electrodes have been evaluated for more than 1,500 operational pulses, making them suitable for long-term and reliable use in both research and clinical studies without a decrease in electroporation efficiency.
– Full Compatibility with Pars Tarava Devices: Gene-electrodes are specifically designed to work with Pars Tarava’s electroporation devices, ensuring seamless and efficient operation. This compatibility guarantees optimal performance, minimal tissue damage during gene transfer, and reproducible results.

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Accessories

To increase productivity and flexibility in using gene-electrodes, a range of specialized accessories is available:

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– Electrode Holder: A tool for securing and precisely positioning the electrodes during electroporation, allowing for adjustable spacing and angle.
– Microgripper to Banana Plug Cable: For secure and quick connection between the gene-electrode and electroporation device. These cables with spring-loaded ends allow for attachment to various points without damaging the sample.
– Holder Stands and Magnetic Stands: To stabilize the electrode setup on the laboratory bench.
– Fine Positioning Stand: For precise three-dimensional positioning of the electrode tip relative to the sample.
– Complete Gene-Electrode Kit: A complete set of electrodes, cables, and holders, packaged for quick and easy use.

These accessories allow users to conduct more precise, reproducible experiments with fewer errors, while enhancing flexibility in different conditions.

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Overall, Pars Tarava’s gene-electrodes, with their engineered design, reusability, high compatibility, and excellent build quality, make them an ideal choice for research centers, universities, and clinical applications in genetics, drug delivery, and biotechnology. The combination of these features ensures superior technical performance compared to disposable or incompatible alternatives, offering broad applications in gene therapy, drug delivery, and electrochemotherapy (ECT) studies.

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For more information and to place an order, please visit the “Contact Us” section on the Pars Tarava website or call our technical support team at +98 902 405 1862 via WhatsApp.

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